You need to visit a gun shop and get a pistol in your hand to answer the fit issue.
Availability of ammo does vary. 9mm, .38, .380, .357, and .44 are the most widly available. .40 and.41 are also fairly easy to get.
I settled on a strategy of having fewest calibers as possible. As I already had a Ruger Blackhawk .357, choice for a short barrel rifle came out to a Henry lever-action chambered for .357.
An advantage of .357 is the ability to use .38.
If you want a pistol the will withstand harsh environment and be dependable, you can't beat a revolver. Some autos are more prone to jamming than others. I have a Ruger P-89 9mm which has a good record for dependability.
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